NUR 455: Alterations In Physiological Integrity II: A Holistic Approach 6 credits This required professional course for baccalaureate nursing students is the second part of an extensive study of holistic nursing care for clients with alterations in physiological integrity. Alterations in Physiological Integrity I: A Holistic Approach is a prerequisite. Students will learn and apply bio-psycho-social-spiritual and cultural theoretical concepts and principles, using the nursing process, in order to care for adult clients experiencing selected alterations in physiological integrity. Emphasis is on nursing care designed to prevent complications and to promote optimal well being in the client and family. Relevant research is incorporated and the legal and ethical components of client care are considered.